Students may feel mentally, emotionally or physically drained usually due to the stress of competitive academic work environment especially when it comes to exams or tests results. Students employ religion copings to cope with these challenges; however studies on the efficacy of religious coping for students dealing with stressful situations have yielded mixed results and literature also lacks the gender differences in the use of positive and negative copings. Therefore the current study was planned to investigate the outcomes of positive and negative religious copings among male and female students. A sample of 370 college students provided data on the measures of positive/negative copings, emotional wellbeing, optimism, self-esteem, anxiety, hopelessness, and suicidality. Chi-square analysis showed that female students used more negative religious copings while male students used the positive religious copings. Findings from multivariate analysis of variance indicated that positive copings were more associated with positive outcomes of high emotional wellbeing, optimism, and self-esteem; and negative copings were found more related to the worse outcomes of greater anxiety, hopelessness, and suicidality. Findings have the greater implications for teachers and students’ counselors in the manner if they guide their students to use positive religious copings instead of negative copings to minimize their academic stress because positive religious copings bring the positive outcomes for students.